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Shyam A. Patel, MD, PhD

Research Focus - Clinico-genomic Profiling and Clonal Dynamic Modeling of Myelodysplastic Syndrome and Acute Myeloid Leukemia

  • Investigating clonal dynamics of TP53-mutant myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML)
  • Exploring the genomics of clonal hematopoiesis of indeterminate potential (CHIP) and associated health risks
  • Understanding the biological heterogeneity among mutation-specific subsets of myeloid neoplasms
 

Representative Publication

Patel SA, Khedr S, Gordon CD, et al. Early identification of TP53 mutations and TP53 allelic state in myelodysplastic neoplasms and acute myeloid leukemia via point-of-care p53 immunohistochemistry. Cancer. 2025;131(13):e35950. 

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