The Mass Spectrometry Facility @ UMass Chan Medical School
Fuller Building
222 Maple Avenue
Shrewsbury, MA 01545
Inquiries
Mass Spectrometry Facility Service Rates
General Rates (Per Hour)
| Category | UMass | External Academic | Corporate |
|---|---|---|---|
| Staff Scientist | $111 | $168 | $233 |
| Director | $165 | $251 | $348 |
| Instrument Time | $172 | $236 | $366 |
Note: All hourly rates require a 1‑hour minimum.
Proteomics (LC‑MS/MS)
| Service | UMass | External Academic | Corporate |
|---|---|---|---|
| Gel Bands (1D/2D Coomassie stained)* | $198 | $303 | $417 |
| Gel Bands — Predigested | $143 | $246 | $361 |
| Gel Bands (silver stained)* | $247 | $352 | $540 |
| Immunopeptidomics | $143 | $246 | $361 |
| Peptide Mapping | $220 | $335 | $464 |
| Short Gel (unresolved protein mixture)* | $312 | $441 | $806 |
| In‑solution Digests (protein mixture)** | $312 | $441 | $806 |
| Complex Digest — Predigested | $252 | $386 | $684 |
| Astral DIA | $345 | $609 | $893 |
| Replicate Runs (quantitative proteomics)*** | $172 | $236 | $488 |
| Alternative Enzymes (PNGase F, Lys‑C, Glu‑C, Asp‑N, Arg‑C) | $64 | $96 | $133 |
| Phosphopeptide enrichment | $150 | $225 | $450 |
| 1D SDS Gels (short or resolved, per gel) | $163 | $224 | $348 |
| Intact Mass Measurement (LC‑MS) | $163 | $256 | $348 |
What’s Included
- In‑gel digests*: Protein reduction/alkylation, digestion, extraction, LC‑MS/MS, database search (unmodified peptides).
- In‑solution/S‑trap digests**: Reduction/alkylation, digestion, cleanup, LC‑MS/MS, informatics (database search for unmodified peptides).
- Replicate runs***: Additional LC‑MS/MS acquisitions for quantitative work (1–2 technical replicates).
Common Workflows
- Protein Identification: LC‑MS/MS (sample preparation + analysis).
- Quantitative Proteomics: LC‑MS/MS + replicate runs + Staff Scientist/Director time (as needed).
- PTM Analysis: LC‑MS/MS + Staff Scientist/Director time.
- Quantitative Targeted Proteomics (PRM/MRM): Contact the Director for project proposal and cost.
Note: Studies requiring protein/peptide labeling, fractionation, or plasma immunodepletion are charged at the Staff Scientist's hourly rate. Reagents, kits, and other materials not included.
Small Molecule Assays
Instrument-Based Services
| Service | UMass | External Academic | Corporate |
|---|---|---|---|
| Instrument Time: Sample Analysis | $89 | $124 | $186 |
| Intact MW‑LCMS | $172 | $236 | $366 |
| Targeted Assay (MRM) Setup | $837 | $1,233 | $1,824 |
Small Molecule Analysis Projects: Projects require a proposal and approval. Have a project idea? Contact the Mass Spectrometry Facility for consultation and an estimate.
Common Workflows
- A. Quantitative Small Molecules
- B. Small Molecule Profiling
- C. HRMS / Small Molecule Mass Measurement
Consumables
- UMass Internal: charged at cost + 15%
- External Academic: charged at cost + 50%
- Corporate: charged at cost + 50%
Items are for project-specific needs and may be purchased and provided by the client.
The Mass Spectrometry Facility @ UMass Chan Medical School
Fuller Building
222 Maple Avenue
Shrewsbury, MA 01545
Inquiries