DCOE Co-Director, Professor of Molecular Medicine, 
The Harvey A. Shultz Chair in Diabetes

Developing & utilizing novel pre-clinical models to observe and identify immune mechanisms that regulate Type 1 diabetes

Exploring immune–beta cell interactions to understand T1D onset

DCOE Co-Director, The William and Doris Krupp Professor of Medicine, Director of Breakthrough T1D Center of Excellence in New England

 
Exploring beta cell biology & anti-beta cell immune responses 

Isolating & sorting pancreatic islet cells from people with diabetes to map gene expression

Professor of Molecular Medicine, Endowed Chair in Diabetes Research

Investigating the role of adipocytes & adipose tissue physiology in Type 2 diabetes pathogenesis

Professor of Molecular Medicine, The Isadore and Fannie Foxman Chair of Medical Research

Studying how insulin signaling controls energy balance at the molecular level

Gene editing to boost insulin signaling and energy use in T2D and obesity

Chair, Program in Molecular Medicine, H. Arthur Smith Chair in Biomedical Research, Howard Hughes Medical Institute Investigator

Our studies of stress signaling pathways have led to the discovery of new genes that contribute to the development of T2D and other metabolic diseases

Assistant Professor of Molecular Medicine

Exploring how metabolic pathways shape the function and survival of beta cells and immune cells in the islet environment, with a focus on anti-inflammatory mechanisms in diabetes & metabolic disease.

Professor of Molecular Medicine, The Herman G. Berkman Chair in Diabetes Care Innovation

Reconstructing Type 1 diabetes in novel preclinical models that allow for the study of human cells & tissues derived from T1D patients. Testing genetically modified stem cell-derived islets to protect them from autoimmune attack.

Professor of Molecular Medicine

Studying the metabolic and growth-related pathways driving insulin resistance in obesity, lipodystrophy, and Type 2 diabetes

Identifying therapies to enhance glucose metabolism and combat insulin resistance in metabolic disease

Associate Professor of Molecular Medicine  

Investigating molecular and cellular mechanisms by which adipocytes regulate systemic glucose and lipid metabolism. Focused on how these regulatory pathways are disrupted in obesity, leading to insulin resistance and type 2 diabetes

Assistant Professor, Program in Molecular Medicine

Studying the molecular and cellular mechanisms that govern beta cell function, survival, and failure under conditions of metabolic stress. 

Associate Professor, Department of Medicine

Professor of Molecular Medicine, Director, Metabolic Disease Research Center

Associate Professor of Molecular Medicine

Professor of Surgery

Investigating hematopoietic stem cell-based therapeutic approaches to treat Type 2 diabetes

Studying the effects of T2D on wound healing and identifying molecular & cellular mechanisms that could lead to potential therapies

Assistant Professor of Vascular Surgery, Medical Director of Lower Extremity Wound Clinic, George and Sybil Fuller Foundation Term Chair in Diabetes

Assistant Professor of Molecular Medicine

Investigating the role of adipose tissue in regulating energy balance & glucose levels throughout the body

Professor of Infectious Diseases and Immunology

Assistant Professor of Molecular Medicine

Focused on innovative strategies to combat obesity, type 2 diabetes, and metabolic dysfunction-associated steatohepatitis (MASH)